Helge Amthor, MD, Prof.

Amthor


MyoGrad Speaker, Versailles
MyoGrad Subproject Speaker, Versailles
Program Coordinator Collège Doctorale franco-allemand

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Phone: +33 1 1704 29229


UFR de la Santé « Simone Veil »,
Université de Versailles Saint-Quentin-en-Yvelines
2, avenue de la source de la bièvre
UFR des Sciences de la Santé
78180 Montigny-Le-Bretonneux
France

Fields of responsibility

MyoGrad – Project 1: Muscle growth regulation



Scientific background

Education

1991-1999
Faculty of Medicine, University of Freiburg

1994-1995
Research student, Department of Anatomy and Developmental Biology,
University College London

1995-1996
Faculty of Medicine Pitié-Salpêtrière, Paris

1994-1999
Research student, Department of Anatomy, University of Freiburg, Germany

Career/Employment

1999-2002
Scientific research assistant and clinical fellow, Department of Pediatrics, University Hospital, Essen, Germany

2002-2005
Postdoctoral fellow of Dr. Ketan Patel at the Royal Veterinary College, University of London, United Kingdom

2005-2006
Scientific research assistant and clinical fellow, Department of Pediatrics, University Hospital, Essen, Germany

2006-2007
Chef de Clinique, Department of Internal Medicine, and Research Fellow, Institut de Myologie, Pitié-Salpêtrière Hospital, Paris, France

2007-2009               
Chef de Clinique, Department of Pediatrics, Groupe Hospitalier Raymond Poincaré, Université Versailles Saint –Quentin-en-Yvelines, France

2009-2012               
MCU-PH (Assistant Professor), Pôle Pédiatrie, CHU Necker Enfants-Malades, Université Paris Descartes

Since Sept 2012      
MCU-PH (Assistant Professor), Service de Pédiatrie, CHU Raymond Poincaré, Université de Versailles St-Quentin-en-Yvelines



Degrees

1986
Professional certificate as a miner, Gera, Germany

1999
Certification (Physician), Stuttgart, Germany

2001
Doctor in Medicine (Dr. med.), University of Freiburg

2007
Diplôme Interuniversitaire de Myologie, Paris

2007
Doctor of Philosophy (PhD), University of London

2007
Board certification for Pediatrics, Düsseldorf and Paris

2010                        
Habilitation à diriger des Recherches



Awards and Honors

1995-1996
Scholarship, DAAD, Bonn, Germany

1996
Scholarship, Behringer Foundation, Freiburg, Germany

1999
Scholarship, Hofmann-La-Roche Foundation, Freiburg

2001
Gödecke-award of the University of Freiburg, Germany

2003
Elsevier-Prize of the World-Muscle-Society

2003
Award of the association "Neuropediatric Research in Germany"

2002-2004
Postdoctoral fellowship from the German Research Council (DFG)

2007-present
Editorial board, Neuromuscular Disorders

2010-present          
Scientific board, Association Française contre les Myopathies



Selected publications

Amthor H, Christ B, Weil M, Patel K. (1998) The importance of timing differentiation during limb muscle development. Curr Biol. 8(11):642-52.

Amthor H, Macharia R, Navarrete R, Schuelke M, Brown SC, Otto A, Voit T, Muntoni F, Vrbova G, Partridge T, Zammit P, Bunger L, Patel K. (2007) Lack of myostatin results in excessive muscle growth but impaired force generation. Proc Natl Acad Sci USA. 104(6):1835-40.

Amthor H, Otto A, Vulin A, Rochat A, Dumonceaux J, Garcia L, Mouisel E, Hourdé C, Macharia R, Friedrichs M, Relaix F, Zammit PS, Matsakas A, Patel K, Partridge T. (2009) Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity. Proc Natl Acad Sci U S A. 106(18):7479-84.

Ono Y, Calbaheu F, Morgan JE, Katagiri T, Amthor H, Zammit PS (2011) BMP signaling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells. Cell Death Differ. 18(2):222-34.

Hoogaars WM, Mouisel E, Pasternack A, Hulmi JJ, Relizani K, Schuelke M, Schirwis E, Garcia L, Ritvos O, Ferry A, t'Hoen PA, Amthor H. (2012) Combined Effect of AAV-U7-Induced Dystrophin Exon Skipping and Soluble Activin Type IIB Receptor in mdx Mice. Hum Gene Ther. 23(12):1269-79.